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Journal Information The American Journal of Nursing (AJN) is the oldest and largest circulating nursing journal in the world. The Journal's mission is to promote excellence in professional nursing, with a global perspective, by providing cutting edge, evidence-based information that embraces a holistic perspective on health and nursing. Clinical articles focus on acute care, health promotion and prevention, rehabilitation, emergencies, critical care, home health care, etc. Columns present additional perspectives on clinical care, such as ethics, the law, practice errors, pain and symptom management, and professional issues. Publisher Information Wolters Kluwer Health is a leading provider of information for professionals and students in medicine, nursing, allied health, pharmacy and the pharmaceutical industry. Major brands include traditional publishers of medical and drug reference tools and textbooks, such as Lippincott Williams & Wilkins and Facts & Comparisons; electronic information providers, such as Ovid Technologies, Medi-Span and ProVation Medical; and pharmaceutical information providers Adis International and Source®. Wolters Kluwer Health is a division of Wolters Kluwer, a leading multi-national publisher and information services company with annual revenues (2005) of €3.4 billion and approximately 18,400 employees worldwide. Wolters Kluwer is headquartered in Amsterdam, the Netherlands. Its depositary receipts of shares are quoted on the Euronext Amsterdam (WKL) and are included in the AEX and Euronext 100 indices. Rights & Usage This item is part of a JSTOR Collection. General High Alert Medication: This medication bears a heightened risk of causing significant patient harm when it is used in error. Pronunciation: Trade Name(s)
Ther. Class. inotropics Pharm. Class. adrenergics IndicationsShort-term (<48 hr) management of heart failure caused by depressed contractility from organic heart disease or surgical procedures. Action Stimulates beta1 (myocardial)-adrenergic receptors with relatively minor effect on heart rate or peripheral blood vessels. Therapeutic Effect(s): Increased cardiac output without significantly increased heart rate. PharmacokineticsAbsorption: Administered by IV infusion only, resulting in complete bioavailability. Distribution: Unknown. Metabolism and Excretion: Metabolized by the liver and other tissues. Half-life: 2 min. TIME/ACTION PROFILE (inotropic effects)
Contraindication/PrecautionsContraindicated in:
Use Cautiously in:
Adverse Reactions/Side EffectsCV: hypertension, increased heart rate, premature ventricular contractions, angina pectoris, arrhythmias, hypotension, palpitations GI: nausea, vomiting Local: phlebitis Neuro: headache Resp: shortness of breath Misc: hypersensitivity reactions, nonanginal chest pain * CAPITALS indicate life-threatening. InteractionsDrug-Drug
Route/DosageIV (Adults and Children): 2.5–15 mcg/kg/min; titrate to response (max dose = 40 mcg/kg/min). IV (Neonates): 2–15 mcg/kg/min. Availability (generic available)Solution for injection (requires dilution): 12.5 mg/mL Premixed infusion: 250 mg/250 mL, 500 mg/250 mL, 1000 mg/250 mL Assessment
Lab Test Considerations: Monitor potassium concentrations during therapy; may cause hypokalemia.
Toxicity and Overdose: If overdose occurs, reduction or discontinuation of therapy is the only treatment necessary because of the short duration of dobutamine. Potential Diagnoses
Implementation
IV Administration
Patient/Family Teaching
Evaluation/Desired OutcomesIncrease in cardiac output.
DOBUTamine is a sample topic from the Davis's Drug Guide. To view other topics, please log in or purchase a subscription. Nursing Central is an award-winning, complete mobile solution for nurses and students. Look up information on diseases, tests, and procedures; then consult the database with 5,000+ drugs or refer to 65,000+ dictionary terms. Complete Product Information. Which findings should the nurse anticipate when assessing a client developing right sided heart failure?The main sign of right-sided heart failure is fluid buildup. This buildup leads to swelling (edema) in your: Feet, ankles and legs.
Which of the following manifestations should the nurse identify as indications of an MI?The key MI signs and symptoms include:. chest pain (with or without radiation to jaw, neck, arm). shortness of breath.. dizziness.. diaphoresis.. atypical symptoms such as nausea, weakness, change in mentation, heartburn, or frequent belching.. ST changes of 1 mm or more.. tachyarrhythmias.. Levine's sign (clutching chest).. |