Which outcome is considered a permanent result of lead poisoning in children?

Lead is a neurotoxic substance that has been shown in numerous research studies to affect brain function and development. Children who have been exposed to elevated levels of lead (>5 ug/dl) are at increased risk for cognitive and behavioral problems during development (CDC, 2012).

Factors which contribute to the risk of lead poisoning:

  • Intensity of exposure (highest lead level)
  • Chronicity or duration of exposure
  • Age of the child during exposure
  • Nutritional and biological status of the child
  • Degree of environmental/ developmental stimulation

Exposure to lead can result in a variety of effects upon neuropsychological functioning including deficits in general intellectual functioning, ability to sustain attention on tasks, organization of thinking and behavior, speech articulation, language comprehension and production, learning and memory efficiency, fine motor skills, high activity level, reduced problem solving flexibility and poor behavioral self-control.

Given the risk of dysfunction, the neuropsychological evaluation assesses the child's cognitive and behavioral functioning with respect to the neurotoxic effects of lead. The kinds of neuropsychological problems resulting from lead poisoning can vary with the nature of the exposure history (intensity, chronicity, age at exposure, etc.) combined with the other contributing risk factors (nutrition, environmental stimulation).

The outcome of these neuropsychological deficits for the child is often quite debilitating and include poor academic learning and performance as well as problems with the development of appropriate social relationships. It is important to understand the child's neuropsychological strengths and deficits in order to reduce the risks of lead poisoning by planning for appropriate developmental, family, educational and behavioral treatment interventions.

Checklist of Possible Neuropsychological Problems Associated with Lead

  • Delayed language or motor milestones (infant, toddler)
  • Poor speech articulation
  • Poor language understanding or usage
  • Problems maintaining attention in school or home
  • High activity level (hyperactivity)
  • Problems with learning and remembering new information
  • Rigid, inflexible problem-solving abilities
  • Delayed general intellectual abilities
  • Learning problems in school (reading, language, math, writing)
  • Problems controlling behavior (e.g., aggressive, impulsive)
  • Problems with fine or gross motor coordination

Real-World Outcomes of Lead Poisoning in Children

Poor Academic Learning and Performance

  • Learning disabilities
  • Problems paying attention
  • Disorganized approach to learning
  • Poor work completion
  • Increased risk to drop out

Poor Social Relationships

  • Communication deficits
  • Impulsive, hyperactive behavior
  • Problems sharing and taking turns
  • Increased aggression
  • Increased need for adult supervision

What Can Be Done?

Prevention

  • Lead-safe housing
  • Education of public, medical and educational communities

Intervention

  • Universal early identification
  • Lead-safe housing
  • Aggressive early medical treatment
  • Aggressive early behavioral treatment
  • Rehabilitation and special education services
  • Adequate nutrition

Children around the world are being poisoned by lead on a massive and previously unrecognized scale.

UNICEF

Lead is a highly poisonous element that is responsible for nearly 1.5 per cent of annual global deaths almost as many deaths as from HIV and AIDS, and more than from malaria.

Nearly a third of the world’s children – up to 800 million children – are affected by lead poisoning.

Lead affects a child’s developing brain, causing decreased intelligence, behavioural disorders and learning problems which can reduce potential earnings in adulthood. It also affects almost every organ in a child’s body, including the heart, lungs and kidneys.

The global magnitude of lead poisoning is only recently coming to light. Here are some findings from a groundbreaking report on lead exposure and its effects on children.

1.    Lead is everywhere

Children can be exposed to lead in various places. It can be found in many consumer products, like water pipes, paint, food cans, spices, cosmetics and traditional medicines. Harder-to-see sources include air, water, food, toys and even the mud children play in. Lead is also used in industries such as mining and battery recycling.

Unborn children can also be exposed to lead through the exposure of their mothers, with adverse development impacts.

2.    Lead exposure is hard to detect

One challenge in detecting childhood lead poisoning is that it is hard to observe and recognize.

At low to moderate levels of exposure, there are typically no symptoms or physical signs apparent to a clinician.

At moderate to high levels of exposure, children may complain of a variety of non-specific symptoms, such as headaches, insomnia, abdominal pain or discomfort, poor attention or loss of appetite.

The impacts of lead poisoning may result in indications of clumsiness, agitation or decreased activity and drowsiness, which can progress to vomiting, convulsions and coma in severe cases.

3.    Lead affects children more than adults

The potential negative effects of lead are far greater for children than for adults.

A child’s brain grows fastest during the early years of childhood, when thousands of neural connections are made every second. Lead exposure can substantially interfere with this complex, important and delicate process.

Infants and young children absorb about 4-5 times more of the lead that enters their bodies than do adults.

The risk of ingesting lead-contaminated soils and dust is also higher, due to the way children play outdoors and because they are closer to the ground, especially when they are learning to walk and crawl.

4.    Lead impacts growth outcomes

Lead exposure can create learning disabilities and challenges that affect children’s executive functioning, impulse control and levels of aggression. These conditions are often irreversible and, studies find, may impact the likelihood of learning and behavioral difficulties, violence, and crime in adulthood.

On a broader scale, all of these factors impact a country’s economic growth, prosperity and security. Accounting for the wide range of effects, a cost-benefit study in the United States found that there was an estimated benefit of $3.10 for every dollar spent in regulatory enforcement to reduce lead hazards.

5.    Even a little means a lot

Lead is a potent neurotoxin that, even with low-level exposure, is associated with a reduction in IQ scores, shortened attention spans and potentially violent and even criminal behaviour later in life. Children under the age of 5 are at the greatest risk of suffering lifelong neurological, cognitive and physical damage, and even death, from lead poisoning.

Older children and adults may also suffer severe consequences from prolonged exposure to lead in food, water and the air they breathe, including increased risk of cardiovascular death and kidney damage later in life. The impact of lead on adults is so large that over 900,000 premature deaths per year are attributed to lead exposure.

6.     Poorer children are at greater risk

It is often the poorest children who are the most severely affected by lead exposure. This is because they are likely to live in areas where exposure risks are higher, such as in places where informal lead-acid battery recycling and smelting operations are more common, near hazardous waste recycling facilities, or in homes that still contain lead in paint or pipes. These children are also more likely to live in areas with little access to health services that help monitor, treat and prevent exposure.

Most of the children impacted by lead live in Africa and Asia, but many are also affected in Central and South America and Eastern Europe.

Since the phase-out of leaded gasoline and gradually of lead-based paint, blood lead levels have declined dramatically in high-income countries. However, these levels for children and adults in low- and middle-income countries continue to be dangerously high.

7.     Prevention is the best cure

Unfortunately, there is no known safe level of lead exposure, and lead poisoning is difficult to cure. Once lead has been in the body for a prolonged period of time, it is very difficult to remove, as it is frequently deposited in bones and teeth. By this point, much of the neurodevelopmental damage has already been done. 

Childhood lead poisoning needs an urgent international response

The potential negative effects of lead poisoning can create irreversible damage for children. With prevention as the only effective way to stop the damage caused by lead poisoning, we must act now.

Pure Earth, Clarios Foundation and UNICEF launched the Protecting Every Child’s Potential (PECP) initiative in October 2020. PECP recognizes that protecting children from lead exposure is critical to their development and their communities – and that addressing this global crisis requires a multi-stakeholder approach, with awareness of local conditions and concern for livelihoods.

PECP works collaboratively with local and national governments, businesses, the United Nations, academia and civil society to reduce exposure to lead.UNICEF also advocates for reduction of childhood lead exposure as a member of the Global Alliance to Eliminate Lead Paint. The alliance promotes the phasing out of paints containing lead through the adoption of lead paint laws.


Messages in this article are taken from the The Toxic Truth, a report jointly published by UNICEF and Pure Earth.

What outcome is considered a permanent result of lead poisoning in children?

Lead exposure can have serious consequences for the health of children. At high levels of exposure lead attacks the brain and central nervous system, causing coma, convulsions and even death. Children who survive severe lead poisoning may be left with intellectual disability and behavioural disorders.

What are the effects of lead poisoning in a child?

Exposure to lead can seriously harm a child's health, including damage to the brain and nervous system, slowed growth and development, learning and behavior problems, and hearing and speech problems.

Is brain damage from lead poisoning permanent?

At high levels, lead can cause permanent damage to the brain and nervous system. This damage can lead to seizures, loss of muscle control, and coma.

Is lead poisoning permanent?

Some of the effects are permanent. In severe cases, anemia, seizures, coma, or death may occur.